Though there are other way of acquiring HIV/AIDS this ONE exceeds others. Timeline of HIV/AIDS . This is a timeline of AIDS, includ...
Though there are other way of acquiring HIV/AIDS this ONE exceeds others. |
Timeline of HIV/AIDS.
This is a timeline of AIDS, including AIDS cases
before 1980.
1930s
:Researchers estimate that sometime in the 1930s a form of simian
immunodeficiency virus, SIV, jumped to humans in central Africa. The mutated
virus became the first human immunodeficiency virus, HIV-1.
1959 :The first known case of HIV in a human
occurs in a person who died in the Congo, later confirmed as having HIV
infection from his preserved blood samples. The authors of the study did not
sequence a full virus from his samples, writing that "attempts to amplify
HIV-1 fragments of >300 base pairs
(bp) were unsuccessful ... However, after numerous attempts, four shorter
sequences were obtained"; these represented small portions of two of the
six genes of the complete HIV genome.
June 28, in New York City, Ardouin Antonio, a
49-year-old Jamaican-American shipping clerk dies of Pneumocystis carinii
pneumonia, a disease closely associated with AIDS. Gordon Hennigar, who
performed the postmortem examination of the man's body, found "the first
reported instance of unassociated Pneumocystis carinii disease in an
adult" to be so unusual that he preserved Ardouin's lungs for later study.
The case was published in two medical journals at the time, and Hennigar has
been quoted in numerous publications saying that he believes Ardouin probably
had AIDS.
1960s : HIV-2, a viral variant found in West
Africa, is thought to have transferred to people from sooty mangabey monkeys in
Guinea-Bissau during this period.
1964 : Jerome Horwitz of Barbara Ann Karmanos
Cancer Institute and Wayne State University School of Medicine synthesize AZT
under a grant from the US National Institutes of Health (NIH). AZT was
originally intended as an anticancer drug.
1966 : Genetic studies of the virus indicate
that, in or about 1966, HIV first arrived in the Americas, infecting one person
in Haiti. At this time, many Haitians were working in Congo, providing the
opportunity for infection.
1968 : A 2003 analysis of HIV types found in the
United States, compared to known mutation rates, suggests that the virus may
have first arrived in the United States in this year. The disease spread from
the 1966 American strand, but remained unrecognized for another 12 years.
1969 : A St. Louis teenager, identified as Robert
Rayford, dies of an illness that baffles his doctors. Eighteen years later,
molecular biologists at Tulane University in New Orleans test samples of his
remains and find evidence of HIV.
1975 : The first reports of wasting and other
symptoms, later determined to be AIDS, are reported in residents of Africa.
1976 : Norwegian sailor Arvid Noe dies; it is
later determined that he contracted HIV/AIDS in Africa during the early 1960s.
1977 :Danish physician Grethe Rask dies of AIDS
contracted in Africa.
A San Francisco prostitute gives birth to the
first of three children who were later diagnosed with AIDS. The children's
blood was tested after their deaths and revealed an HIV infection. The mother
died of AIDS in May 1987. Test results show she was infected no later than
1977.
1978 :A Portuguese man known as Senhor José
(English: Mr. Joseph) dies; he will later be confirmed as the first known
infection of HIV-2. It is believed that he was exposed to the disease in
Guinea-Bissau in 1966.
1979
An early case of AIDS in the United States was of
a female baby born in New Jersey in 1973 or 1974. She was born to a
sixteen-year-old girl, an identified drug-injector, who had previously had
multiple male sexual partners. The baby died in 1979 at the age of five. Subsequent
testing on her stored tissues confirmed that she had contracted HIV-1.
1980
April 24, San Francisco resident Ken Horne, the
first AIDS case in the United States to be recognized at the time, is reported
to the Center for Disease Control with Kaposi's sarcoma (KS). He was also
suffering from Cryptococcus.
October 31, French-Canadian flight attendant
Gaëtan Dugas pays his first known visit to New York City bathhouses. He would
later be deemed "Patient Zero" for his apparent connection to many
early cases of AIDS in the United States.
December 23, Rick Wellikoff, a Brooklyn
schoolteacher, dies of AIDS in New York City. He is the 4th US citizen to die
from the disease.
1981 :[1]January
15, Nick Rock becomes the first known AIDS death in New York City.
May 18, Lawrence Mass becomes the first
journalist in the world to write about the epidemic, in the New York Native, a
gay newspaper. A gay tipster overheard his physician mention that some gay men
were being treated in intensive-care units in New York City for a strange
pneumonia. "Disease Rumors Largely Unfounded" was the headline of Mass's
article. Mass repeated a New York City public-health official's claims that
there was no wave of disease sweeping through the gay community. At this point,
however, the Centers for Disease Control (CDC) had been gathering information
for about a month on the outbreak that Mass's source dismissed.
June 5, The CDC reports a cluster of Pneumocystis
pneumonia in five gay men in Los Angeles.
July 3, An article in the New York Times carries
the headline: "Rare Cancer Seen in 41 Homosexuals". The article describes
cases of Kaposi's sarcoma found in forty-one gay men in New York City and San
Francisco.
July 4, The CDC reports clusters of Kaposi's
sarcoma and Pneumocystis pneumonia among gay men in California and New York[2]
City.
First known case in the United Kingdom.
One of the first reported patients to have died
of AIDS (presumptive diagnosis) in the US is reported in the journal
Gastroentereology. Louis Weinstein, the treating physician, commented that
"Although no clear-cut evidence of immuno-deficiency could be demonstrated
in our patient, this could not be ruled out completely.
By the end of the year, 121 people are known to
have died from the disease.
1982 :June 18, "Exposure to some substance
(rather than an infectious agent) may eventually lead to immunodeficiency among
a subset of the homosexual male population that shares a particular style of
life." For example, Marmor et al. recently reported that exposure to amyl
nitrite was associated with an increased risk of KS in New York City. Exposure to
inhalant sexual stimulants, central-nervous-system stimulants, and a variety of
other "street" drugs was common among males belonging to the cluster
of cases of KS and PCP in Los Angeles and Orange counties."
July 9, The CDC reports a cluster of
opportunistic infections (OI) and Kaposi's sarcoma among Haitians recently
entering the United States.
July 27, The term AIDS (acquired immune
deficiency syndrome) is proposed at a meeting in Washington of gay-community
leaders, federal bureaucrats and the CDC to replace GRID (gay-related immune
deficiency) as evidence showed it was not gay specific.
Summer, First known case in Italy.
September 24, The CDC defines a case of AIDS as a
disease, at least moderately predictive of a defect in cell-mediated immunity,
occurring in a person with no known cause for diminished resistance to that
disease. Such diseases include KS, PCP, and serious OI. Diagnoses are
considered to fit the case definition only if based on sufficiently reliable
methods (generally histology or culture). Some patients who are considered AIDS
cases on the basis of diseases only moderately predictive of cellular
immunodeficiency may not actually be immunodeficient and may not be part of the
current epidemic.
December 10, a baby in California becomes ill in
the first known case of contracting AIDS from a blood transfusion.
First known case in Brazil.
First known case in Canada.
First known case in Australia, diagnosed at St
Vincent's Hospital, Sydney.
1983 : January, Françoise
Barré-Sinoussi, at the Pasteur Institute in Paris, isolates a retrovirus
that kills T-cells from the lymph system of a gay AIDS patient. In the
following months, she would find it in additional gay and hemophiliac
sufferers. This retrovirus would be called by several names, including LAV and
HTLV-III before being named HIV in 1986.
CDC National AIDS Hotline is established.
March, United States Public Health Service (PHS
or USPHS) issues donor screening guidelines. AIDS high-risk groups should not
donate blood/plasma products.
First AIDS-related death occurs in Australia, in
the city of Melbourne. The Hawke Labor government invests in a significant
campaign that has been credited with ensuring Australia has one of the lowest
HIV infection rates in the world.
AIDS is diagnosed in Mexico for the first time.
HIV can be traced in the country to 1981.
The PCR (polymerase chain reaction) technique is
developed by Kary Mullis; it is widely used in AIDS research.
Within a few days of each other, the musicians
Jobriath and Klaus Nomi become the first internationally-known recording
artists to die from AIDS-related illnesses.
First known case in Portugal.
1984 : March 30, Gaëtan Dugas dies. He was a
French Canadian flight attendant linked by the CDC directly or indirectly to 40
of the first 248 reported cases of AIDS in the U.S.
April 23, U.S. Health and Human Services
Secretary Margaret Heckler announces at a press conference that an American
scientist, Robert Gallo, has discovered the
probable cause of AIDS: the retrovirus is subsequently named human
immunodeficiency virus or HIV in 1986. She also declares that a vaccine will be
available within two years.
June 25, French philosopher Michel Foucault dies
of AIDS in Paris.
September 6, First performance at Theatre Rhinoceros
in San Francisco of The AIDS Show which runs for two years and is the subject
of a 1986 documentary film of the same name.
December 17, Ryan White was diagnosed with AIDS
by a doctor performing a partial lung removal. White became infected with HIV
from a blood product, known as Factor VIII, which was administered to him on a
regular basis as part of his treatment for hemophilia. When the public school
that he attended, Western Middle School in Russiaville, Indiana, learned of his
disease in 1985 there was enormous pressure from parents and faculty to bar him
from school premises. Due to the widespread fear of AIDS and lack of medical
knowledge, principal Ron Colby and the school board assented. His family filed
a lawsuit, seeking to overturn the ban.
1985
March 2, FDA approves the first AIDS antibody
screening tests for use on all donated blood and plasma intended for
transfusion and product manufacture.
October 2, Rock Hudson
dies of AIDS. On July 25, 1985, he was the first American celebrity to publicly
admit having AIDS; he had been diagnosed with it on June 5, 1984.
October 12, Ricky Wilson, guitarist of American
rock band The B-52's dies from an AIDS related illness. The album Bouncing Off
The Satellites, which he was working on when he died, is dedicated to him when
it is released the next year. The band is devastated by the loss and do not
tour or promote the album. Wilson is eventually replaced on guitar by his
former writing partner Keith Strickland, the B52's former drummer.
October, a conference of public health officials
including representatives of the Centers for Disease Control and World Health
Organization meet in Bangui and define AIDS in Africa as "prolonged fevers
for a month or more, weight loss of over 10% and prolonged diarrhea".
First officially reported cases in China.
November 11, An Early Frost, the first film to
cover the topic of HIV/AIDS is broadcast in the U.S. on prime time TV by NBC.
1986
HIV (human immunodeficiency virus) is adopted as
name of the retrovirus that was first proposed as the cause of AIDS by Luc Montagnier of France, who named it LAV
(lymphadenopathy associated virus) and Robert Gallo of
the United States, who named it HTLV-III (human T-lymphotropic virus type III)
January 14, "one million Americans have
already been infected with the virus and that this number will jump to at least
2 million or 3 million within 5 to 10 years..." – NIAID Director Anthony
Fauci, New York Times.
February, President Reagan instructs his Surgeon
General C. Everett Koop to prepare a report on AIDS. (Koop was excluded from
the Executive Task Force on AIDS established in 1983 by his immediate superior,
Assistant Secretary of Health Edward Brandt.) Without allowing Reagan's
domestic policy advisers to review the report, Koop released the report at a
press conference on
October 22, 1986. Attorney Geoffrey Bowers is
fired from the firm of Baker & McKenzie after AIDS-related Kaposi's sarcoma
lesions appeared on his face. The firm maintained that he was fired purely for
his performance.He sued the firm, in one of the first AIDS discrimination cases
to go to a public hearing. These events were the inspiration for the 1993 film
Philadelphia.
November 18, model Gia Carangi dies of
AIDS-related illness.
First officially known cases in the Soviet Union
and India.
1987: AZT (zidovudine),
the first antiretroviral drug, becomes available to treat HIV.
On February 4, popular performing musician
Liberace dies from AIDS related illness.
On May 28, playwright and performer Charles
Ludlam dies of AIDS-related PCP pneumonia.
On July 11, Tom Waddell, founder of the Gay
Games, dies of AIDS.
Randy Shilts investigative journalism book And
the Band Played On: Politics, People, and the AIDS Epidemic published
chronicling the 1980–1985 discovery and spread of HIV/AIDS, government
indifference, and political infighting in the United States to what was
initially perceived as a gay disease. (Shilts himself would die of the disease
on February 17, 1994.)
1988
May, C. Everett Koop sends an eight-page,
condensed version of his Surgeon General's Report on Acquired Immune Deficiency
Syndrome report named Understanding AIDS to all 107,000,000 households in the
United States, becoming the first federal authority to provide explicit advice
to US citizens on how to protect themselves from AIDS.
November 11, The fact-based AIDS-themed film Go
Toward The Light is broadcast on CBS.
December 1,1988, The first World AIDS
Day takes place.
In Buenos Aires, Argentina, the rock musicians
Miguel Abuelo (March 26) and Federico Moura (December 21), die from
AIDS-related complications.
1989: The television movie The Ryan White Story
airs. It stars Judith Light as Jeanne, Lukas Haas as Ryan and Nikki Cox as
sister Andrea. Ryan White had a small cameo appearance as Chad, a young patient
with AIDS. Another AIDS-themed film, The Littlest Victims, debuted in 1989,
biopicing James Oleske, the first U.S. physician to discover AIDS in newborns
during AIDS' early years, when many thought it was only spread through
homosexual sex.
NASCAR driver Tim Richmond dies from AIDS-related
complications.
1990 : January 6,
British actor Ian Charleson dies from AIDS at the age of 40 — the first
show-business death in the United Kingdom openly attributed to complications from
AIDS.
February 16, New York artist and social activist
Keith Haring dies from AIDS-related illness.
April 8, Ryan White
dies at the age of 18 from pneumonia caused by complications associated with
AIDS.
Congress enacted The Ryan White Comprehensive AIDS
Resources Emergency (CARE) Act or Ryan White Care Act, the United States'
largest federally funded health related program (excluding Medicaid and
Medicare).
July 7, Brazilian singer Cazuza dies in Rio de
Janeiro at the age of 32 from an AIDS-related illness.
1991
November 7, NBA star Magic Johnson publicly
announces that he is HIV-positive.
November 24, A little over 24 hours after issuing
a statement confirming that he had been tested HIV positive and had AIDS,
Freddie Mercury (singer of the British band Queen) dies at the age of 45. The
official cause of death is bronchial pneumonia resulting from AIDS.
1992 : The first
combination drug therapies for HIV are introduced. Such
"cocktails" are more effective than AZT alone and slow down the
development of drug resistance.
April 6, popular science fiction writer Isaac
Asimov dies. Ten years later, his wife revealed that his death was due to
AIDS-related complications. The writer was infected during a blood transfusion
in 1983.[38]
June 18, Australian singer Peter Allen dies from
complications due to AIDS.
September 12, American actor Anthony Perkins,
known for his role as Norman Bates in the Psycho movies, dies from AIDS.
At the Royal Free Hospital in London, an
out-patients' centre for HIV and AIDS is opened by Ian McKellen. It is named
the Ian Charleson Day Centre after actor Ian Charleson.
Robert Reed, best known as Mike Brady on the
sitcom The Brady Bunch dies of AIDS on May 12.
1993 : Tennis star Arthur Ashe dies from
AIDS-related complications.
1994 : Elizabeth Glaser, wife of Starsky &
Hutch's Paul Michael Glaser, dies from AIDS-related complications almost ten
years after receiving an infected blood transfusion while giving birth. She
unknowingly passes AIDS on to her daughter, Ariel, and son, Jake. Ariel died in
1988, Jake is living with HIV, while Paul Michael remains negative.
1995 : Saquinavir, a new
type of protease inhibitor drug, becomes available to treat HIV. Highly active
antiretroviral therapy (HAART) becomes possible.Within two years, death
rates due to AIDS will have plummeted in the developed world.
March 26, Rapper Eazy-E dies from AIDS-related
pneumonia.
April 4, British DJ and entertainer Kenny Everett
dies from AIDS.
Oakland resident Jeff
Getty becomes the first person to receive a bone
marrow transplant from a Baboon as an experimental procedure to treat his HIV
infection. The graft did not take, but Getty experienced some reduction
in symptoms, before dying of heart failure after cancer treatment, in 2006.
1996 : Robert Gallo Robert Gallo's discovery that
some natural compounds known as chemokines can
block HIV and halt the progression of AIDS is hailed by Science as one of that
year's most important scientific breakthroughs.
1997: September 2, The Washington Post carries an
article stating, "The most recent estimate of the number of Americans
infected (with HIV), 750,000, is only half the total that government officials
used to cite over a decade ago, at a time when experts believed that as many as
1.5 million people carried the virus."
Based on the Bangui definition the WHO's
cumulative number of reported AIDS cases from 1980 through 1997 for all of
Africa is 620,000. For comparison, the cumulative total of AIDS cases in the
USA through 1997 is 641,087.
December 7, "French President Jacques Chirac
addressed Africa's top AIDS conference on Sunday and called on the world's
richest nations to create an AIDS therapy support fund to help Africa. According to Chirac, Africa
struggles to care for two-thirds of the world's persons with AIDS without the
benefit of expensive AIDS therapies. Chirac invited other countries, especially
European nations, to create a fund that would help increase the number of AIDS
studies and experiments. AIDS workers welcomed Chirac's speech and said they hoped
France would promote the idea to the Group of Eight summit of the world's
richest nations."
1998
December 10, International Human Rights Day,
Treatment Action Campaign (TAC) is launched to campaign for greater access to
HIV treatment for all South Africans, by raising public awareness and
understanding about issues surrounding the availability, affordability and use
of HIV treatments. TAC campaigns against the view that AIDS is a death
sentence.
1999
January 31, Studies suggest that a retrovirus,
SIVcpz (simian immunodeficiency virus) from the common chimpanzee Pan
troglodytes, may have passed to human populations in west equatorial Africa
during the twentieth century and developed into various types of HIV.
Edward Hooper releases a book called The River,
which accuses doctors who developed and administered the oral polio vaccine in
1950s Africa of unintentionally starting the AIDS epidemic. The OPV AIDS
hypothesis receives a great deal of publicity. It was later refuted by studies
demonstrating the origins of HIV as a mutated variant of a simian
immunodeficiency virus that is lethal to humans. Hooper's hypothesis should not
be confused with the Heart of Darkness origin theory.
2000 : World Health Organization estimates
between 15% and 20% of new HIV infections worldwide are the result of blood
transfusions, where the donors were not screened or inadequately screened for
HIV.
2001: September 21, FDA licenses the first
nucleic acid test (NAT) systems intended for screening of blood and plasma
donations.
2004: January 5, "Individual risk of
acquiring HIV and experiencing rapid disease progression is not uniform within
populations", says Anthony S. Fauci, the director of NIAID.
2005: January 21, The CDC recommends
anti-retroviral post-exposure prophylaxis for people exposed to HIV from rapes,
accidents or occasional unsafe sex or drug use. This treatment should start no
more than 72 hours after a person has been exposed to the virus, and the drugs
should be used by patients for 28 days. This emergency drug treatment has been
recommended since 1996 for health-care workers accidentally stuck with a
needle, splashed in their eyes with blood, or exposed in some other way on the
job.
A highly resistant strain of HIV linked to rapid
progression to AIDS is identified in New York City.[
2006: November 9, SIV found in gorillas.
2007: The first case of someone being cured of
HIV is reported. A San Francisco man, Timothy Ray Brown, suffering from
leukemia and HIV, is cured of HIV through a bone
marrow transplant in Germany. Other similar cases are being studied to
confirm similar results.Maraviroc, the first
available CCR5 receptor antagonist, is approved by the FDA as an antiviral drug
for the treatment of AIDS.
2011: Confirmation is published that the first
patient cured of HIV, Timothy Ray Brown, still has a negative HIV status, 4
years after treatment.
2013: Confirmation is published that a toddler
has been "functionally cured" of HIV infection.[54]
A New York Times Article says that 12 people of
75 who began combination antiretroviral therapy soon after becoming infected
may have been "functionally cured" of HIV according to a French
study. A functionally cured person will not experience an increase of the virus
in the bloodstream despite stopping antiretroviral therapy, and therefore not
progress to AID.
Source: Wikipedia
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